Introduction: The hyper-catabolic state is a devastating pathophysiological response to severe injury, infection or burns. Nandrolone decanoate (ND) is a potent anabolic steroid have many clinical indications, but not investigated in burn injuries yet. Patients and methods: A prospective randomized control study included 40 burned patients who were treated in Burn unit from burn injuries ranged from 20 to 40%. Both groups are objectively assessed, clinically and laboratory during treatment period till full recovery from burns’ injury. Recall assessment of the drug safety after many years is

Background: Taurine-upregulated gene 1 (TUG1) is one of the long noncoding RNAs (lncRNAs) that plays a role in melanogenesis. MicroRNA-377 (miRNA-377) is a conserved noncoding RNA that regulates angiogenesis and promotes oxidative stress. Peroxisome proliferator-activated receptors (PPARs) are components of the nuclear hormone receptor superfamily. PPAR-γ activators stimulate melanogenesis. Interleukin (IL)-17 has been implicated in the pathogenesis of several immunological diseases. This work aimed at detecting the expression levels of lncRNA TUG1, miRNA-377, PPAR-γ, and IL-17 among vitiligo

Background: Data have been accumulating in the past few years that identify vitiligo as a disorder with systemic implications. Results and methods: In this hospital-based, cross-sectional, case–control study, 50 patients with non-segmental vitiligo and 50 age- and sex-matched controls underwent analysis of serum lipid profile, oxidative stress biomarkers and carotid duplex. Hydrogen peroxide (H2O2) and malondialdehyde (MDA) were significantly higher in patients than controls (p-value <.001, <.001, respectively); on the other hand, total antioxidant capacity (TAC) was significantly lower in

Cellular respiration is an important process performed by mitochondria. Nad complex is the major complex involved in this process and one of the main subunits in this complex is the nad7 (nad dehydrogenase subunit 7). In Hordeum vulgare subsp. spontaneum, four nad7 cDNAs are described at 500 mM salinity, 0 h, or control (GenBank accession no. MW433884), after 2 h (GenBank accession no. MW433885), after 12 h (GenBank accession no. MW433886) and after 24 h (GenBank accession no. MW433887). Twenty six RNA editing sites were revealed in positions: C44, C45, C77, C83, C99, C137, C224, C244, C251

Fuzzy C-Means (FCM) clustering technique is among the most effective partitional clustering algorithms available in the literature. The Capacitated Vehicle Routing Problem (CVRP) is an important industrial logistics and managerial NP-hard problem. Cluster-First Route-Second Method (CFRS) is one of the efficient techniques used to solve CVRP. In CFRS technique, customers are first divided into clusters in the first phase, then each cluster is solved independently as a Traveling Salesman Problem (TSP) in the second phase. This research is concerned with the clustering phase of CFRS, and TSP is

It is feasible and safe to use unmanned aerial vehicle (UAV) as the data collection platform of the Internet of things (IoT). In order to save the energy loss of the platform and make the UAV perform the collection work effectively, it is necessary to optimize the deployment of UAV. The objective problem is to minimize the sum of the lost energy of UAV and the loss of data transmission of Internet of things devices. The key to solving the problem is to calculate the location of the docking points and the number of docking points when the UAV is working to collect data. This paper proposes a

Much research has focused on the development of optimal strategies for rehabilitation and replacement of water and sewer infrastructures. Condition assessment is an integral component in any asset management program for assessing the asset physical condition. Determining the condition of buried infrastructure tends to be cumbersome, costly and error-prone. As such, decision makers must balance the value of obtained information through condition assessments with the cost of obtaining this information. Such decisions must balance between conflicting needs and need to consider the sought level of

Nano particles contribute as a partial substitute in the production of eco-friendly building materials. This research presents a quantitative assessment of the sustainability effect of partially replacing cement in the green concrete mix with two types of nano-waste particles. The assessment is achieved using two weighing criteria developed by a Sustainable Decision Support System (SDSS) model. This assesses the alternatives using scoring systems based on both the Life Cycle Assessment (LCA) technique and Multi-Criteria decision analysis method. Ten sustainable aspects comprising four

This paper represents modeling and control of an agricultural service skid steering mobile robot for the purposes of grass cutting using Proportional-Integral-Derivative (PID) controller and Fuzzy Logic techniques and feedback signals from sensors as IMU, encoders, and Machine Vision. The paper deals with the system modeling into two methods: The first is using Fuzzy modeling as a modeling tool for complex nonlinear system, the second is using MATLAB software system Identification Tool. The study Uses PID, Fuzzy logic controller and fuzzy self-tuning of PID controller to control the path

In this paper a novel strategy for the position control and trajectory tracking of robotic manipulators is proposed. This strategy consists of an independent two degree of freedom PID controller for a two links robotic arm. Due to the capability of two degree of freedom PID controllers to deal with disturbances, each link is controlled independently considering that the disturbance does not affect the system performance due to the robustness of the closed loop system. Then, a fuzzy type-2 centralized compensator is implemented to drive the orientation variables with the desired trajectory in