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Evaluation of Different Sudan Dyes in Egyptian Food Samples Utilizing Liquid Chromatography/Tandem Mass Spectrometry
A sensitive and a precise method was developed for the quantification of different Sudan dyes in some Egyptian food samples. They were analyzed utilizing two-fragment ion transition under multiple reaction monitoring (MRM) mode. Separation was carried out on Kinetex 2.6u C18 100 A (75 mm × 4.6 mm) phenomenex using isocratic elution with 10:90% water and acetonitrile containing 2.0 mmol/L ammonium formate and 0.2% formic acid. The validation parameters were obtained and verified. The linearity was 0.2–10.0 ng/mL with r2 > 0.9975. LOD and LOQ were 0.06 and 0.19 ng/mL, respectively, for Sudan (I
Mathematical analysis of gene regulation activator model
This paper presents a complete analysis of the mathematical model of the gene regulation process. The model describes the induced gene expression under the effect of activators. The model differential equations are solved analytically, and the exact solution of the gene model is introduced. Moreover, a study of the model dynamics, including the fixed points and stability conditions are presented. The parameters effects on the phase plane portraits and the transient responses of the mRNA as well as the protein concentrations are intensively detailed. This work serves as a brick stone towards a
Biohybrid soft robots, E-skin, and bioimpedance potential to build up their applications: A review
Soft Robotics is a new approach towards better human-robot interaction and biomimicry in the robotics field. Its integration with biological materials (Biohybrid soft robotics) is one of the topics being focused on in the soft robotics research in the last fifteen years. The motive for this approach is to combine the best of biological and artificial systems. In this article, Biohybrid soft robots and Electronic Skin (E-skin), which is considered one of the advances of soft robotics, are reviewed. Their most significant milestones and the highlights of their most researched applications are
Simple implementations of fractional-order driving-point impedances: Application to biological tissue models
A novel procedure for the circuit implementation of the driving-point impedance of frequency-domain material models, constructed from fractional-order elements of arbitrary type and order, is introduced in this work. Following this newly introduced concept, instead of emulating separately each fractional-order element in the model under consideration, the direct emulation of the complete model can be achieved through the approximation of the total impedance function. The magnitude and phase frequency responses of the impedance function are first extracted and approximated through curve-fitting
Design of fractional-order differentiator-lowpass filters for extracting the R peaks in ECG signals
An implementation of a fractional-order differentiator-lowpass filter is presented in this work, which is constructed from Operational Transconductance Amplifiers as active cells. This offers the benefits of electronic tuning and, also, of monolithic implementation. The presented scheme has been employed for the extraction of the R peaks in electrocardiogram signals due to its efficiency for performing this task even in a noisy environment. The provided post-layout simulation results confirm the correct operation of this solution as well as its reasonable sensitivity characteristics. © 2019
A current-mode system to self-measure temperature on implantable optoelectronics
Background: One of the major concerns in implantable optoelectronics is the heat generated by emitters such as light emitting diodes (LEDs). Such devices typically produce more heat than light, whereas medical regulations state that the surface temperature change of medical implants must stay below + 2 °C. The LED's reverse current can be employed as a temperature-sensitive parameter to measure the temperature change at the implant's surface, and thus, monitor temperature rises. The main challenge in this approach is to bias the LED with a robust voltage since the reverse current is strongly
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